Primary platinum refractory disease
WebIndeed, treatment options in platinum refractory disease included monochemotherapy with taxanes and methotrexate, ... However, head and neck second malignancies could occurr for impaired immunosurveillance. Recurrent disease with a primary induced resistance to immunotherapy is the result of an incomplete and ineffective first immune response. WebJan 31, 2011 · CathyAsh. Jan 31, 2011 • 10:40 AM. Here's my understanding: Platinum refractory: cancer grew while on platinum therapy. Platinum resistant: recurrance within 6 …
Primary platinum refractory disease
Did you know?
WebPatients that develop platinum refractory disease are good candidates for clinical trials in ... These studies certainly provide evidence that support primary re-treatment with platinum … WebThe subgroup of patients without primary platinum-refractory disease and with 1-3 prior lines of therapy (“phase 3 population”) comprised 137 patients, of whom 46 received NP …
WebMar 30, 2024 · By chance, more women with either primary platinum-refractory disease or who had already received four or more prior lines of therapy, both indicators of a very poor … WebOct 25, 2024 · Patient has primary platinum-refractory disease or primary platinum resistance, defined as disease progression during first-line platinum-based therapy …
WebNov 30, 2024 · If patients had primary platinum-refractory disease, or received previous treatment with an anti-CD47, anti-SIRPα targeting agent, or a CD40 agonist, they were … WebJul 1, 2024 · Platinum-Refractory Primary Peritoneal Carcinoma; Recent clinical studies. Etiology. HIPEC after neoadjuvant chemotherapy and interval debulking is associated with …
Web19 hours ago · In the population with platinum-refractory disease, the TIA-GEP score was balanced between arms; however, in the population with platinum-eligible disease, there was an imbalance in TIA-GEP scores, with a higher proportion of patients with a TIA-GEP score of 10 or higher in the nivolumab arm (47.5%) versus the nivolumab plus ipilimumab arm …
WebJan 31, 2024 · The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. … how to address email for job applicationWebMar 31, 2024 · To date, there are no validated predictive markers of primary platinum refractory or resistant disease. Although limited and biologically unfounded, the time since the last platinum chemotherapy currently defines resistance (≤ 6 months) or sensitivity (> 6 months) to the treatment in HGSOC patients that experience recurrent disease [25, 26]. how to address envelopes on windows 10WebDec 1, 2024 · Relapsed lymphoma is a disease that responded to treatment initially, but then returned. Refractory disease means the cancer hasn’t responded to the initial treatment … how to address envelope in google docsWebOct 9, 2016 · Platinum-refractory disease in the context of primary therapy refers to cancer progression within 6 months after platinum therapy administered in the context of … how to address employee gossipWebA phase 3 trial evaluating intermittent RELA + NP vs investigator’s choice of chemotherapy in patients without primary platinum-refractory disease is ongoing (NCT05257408). Clinical … metin2 account kaufen teutoniaWebAug 10, 2012 · Patients with recurrent ovarian cancer who have a complete response to initial chemotherapy and a treatment-free interval <6 months demonstrate ‘platinum … how to address envelope for bridal showerWebMar 14, 2024 · Forty percent of the women had suboptimally resected stage III disease, and 26% had stage IV disease. The primary end point of the study was PFS.[Level of evidence B1] ... Responses have been observed … metin2 4yours