WebACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition Ferroptosis is a form of regulated necrotic cell death controlled by glutathione peroxidase 4 (GPX4). At … WebAcsl4 is a member of the long-chain fatty-acid-coenzyme A ligase family. All the members of this family have different substrate specificity, subcellular localization, and tissue …
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WebFeb 8, 2024 · Acyl-CoA synthetase long-chain family member 4 (ACSL4), which is a key enzyme that regulates lipid composition, has been shown to contribute to the execution of ferroptosis, but its role in I/R ... WebFeb 1, 1998 · FACL4 encodes a predicted protein product of 670 amino acids (711 in brain), with a remarkable level of conservation compared to the rat acyl-CoA synthetases ACS4 and brain-specific ACS3 protein sequences. We are investigating the possibility that the absence of this enzyme may play a role in the development of mental retardation or …
WebACSL4 Antibody (F-4) is a mouse monoclonal IgG 1 κ ACSL4 antibody, cited in 56 publications, provided at 200 µg/ml. raised against amino acids 623-675 mapping near … WebApr 6, 2024 · BackgroundIschemic stroke is the main cause of disability worldwide, leading to a serious socioeconomic burden. Ferroptosis is a non-apoptotic form of programmed cell death and is related to various diseases. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is considered a target of ferroptosis, but its specific role in ischemic stroke …
The FACL4 pathway is also important in colon carcinogenesis; the development of selective inhibitors for FACL4 may be a worthy effort in the prevention and treatment of colon cancer. FACL4 up-regulation appears to occur during the transformation from the cancer from adenoma to adenocarcinoma. See more Long-chain-fatty-acid—CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme See more The ACSL4 gene is located on the X-chromosome, with its specific location being Xq22.3-q23. The gene contains 17 exons. ASCL4 encodes a 74.4 kDa protein, FACL4, … See more The most common SNP (C to T substitution) in the first intron of the FACL4 gene is associated with altered FA composition of … See more • Knights KM, Jones ME (1992). "Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs". Biochem. … See more Fatty acid-CoA ligase 4 (FACL4), the protein encoded by the ACSL4 gene, is an acyl-CoA synthetase, which is an essential class of lipid … See more ACSL4 expression is regulated by SHP2 activity. Additionally, ACSL4 interacts with ACSL3, APP, DSE, ELAVL1, HECW2, MINOS1, PARK2, SPG20, SUMO2, TP53, TUBGCP3 See more • Human ACSL4 genome location and ACSL4 gene details page in the UCSC Genome Browser. See more WebDefects in ACSL4 are the cause of mental retardation X-linked type 63 (MRX63) [MIM:300387]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. ... FACL4 was immunoprecipitated …
WebAnti-ACSL4 antibodies are offered by a number of suppliers. This target gene encodes the protein 'acyl-CoA synthetase long chain family member 4' in humans and may also be known as ACS4, FACL4, LACS4, MRX63, long-chain-fatty-acid--CoA ligase 4, and acyl-CoA synthetase 4. Structurally, the protein is reported to be 79.2 kilodaltons in mass.
WebBoster Bio Anti-FACL4/ACSL4 Antibody Picoband™ catalog # A04372-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody. note cards in tinWebACSL4. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. ACSL4 INFORMATION. Proteini. Full gene name according to HGNC. Acyl-CoA synthetase long chain family member 4. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. ACSL4 (ACS4, FACL4, LACS4, MRX63, … note cards holder office maxnote cards from photosWebACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) Antibody Reactivity: Human Applications: ICC, IF, IHC, IHC-P, WB Format: Unconjugated Price: 400 µl/$393 Select … note cards boxWebTurboCHO™ High Throughput Services as fast as 2 weeks; TurboCHO™ Protein Expression in Singapore as fast as 8 BDs; TurboCHO™ Protein Expression Upgraded; MonoRab™ Rabbit mAb; Anti-idiotype Antibody Services New!; Neoantigen Peptide Service New! CRISPR sgRNA Services note cards for charityWebSep 23, 2016 · Here, we show that acyl-CoA synthetase long-chain family member 4 (ACSL4) is required for ferroptotic cancer cell death. Compared with ferroptosis-sensitive … note cards in mla formatWebAnti-FACL4 antibody See all FACL4 primary antibodies Description Goat polyclonal to FACL4 Host species Goat Tested applications Suitable for: WB, IHC-P more details … note cards from artwork