WebDec 22, 2008 · The first-day dose of echinocandin therapy (vs. subsequent days) was most strongly associated with mean daily dose. Conclusions: In hospital practice, the mean … WebTreatment of candidemia with echinocandins: data on hospital resource use from a real world setting Fluconazole before or after echinocandin was associated with significantly greater resource utilization than echinocandin use alone.
Treatment of candidemia with echinocandins: data on hospital …
WebAzoles and echinocandins are antifungal drugs used globally to treat Candida infections. However, resistance to these antifungal drugs has increased in many of the Candida species, and the effects this has in the clinical setting can be seen. Objectives WebMar 25, 2024 · Echinocandin therapy was commonly prescribed in critically ill patients with risk factors for IFD. Although the majority of prescriptions were empiric and compliant with local guidelines, improved guidelines incorporating additional patient factors should be included in future antifungal stewardship initiatives. CONFLICTS OF INTEREST … computer technician employment outlook
Notes from the Field: Transmission of Pan-Resistant …
WebHospital mortality was significantly higher in the echinocandin-only group compared to the fluconazole-echinocandin group (35.2% vs 23.7%, p = 0.015), further establishing that these patients were more acutely ill. Unadjusted readmission rates within 30 days among patients discharged alive were not different between study groups. WebAug 5, 2009 · Echinocandins have a low potential for drug–drug interactions, given the lack of involvement of CYP450 enzymes in the metabolism of echinocandins. The reported interactions are summarized in Table 2. Caspofungin undergoes slow metabolism by nonenzymatic processes in the liver and is a poor substrate for CYP450 enzymes. WebSep 15, 2010 · An echinocandin should be the initial treatment in critically ill patients. Amphotericin B is not recommended as initial therapy because of its toxicity. ANTI-ENTEROCOCCAL THERAPY Antimicrobial... econofitness greenfield park